Fellows;The Provost; Scholars and other Members of Board of Trinity College Dublin
发明人:
Matthew Campbell,Peter Humphries,Jeffrey O'Callaghan
申请号：
US16264095
公开号：
US20190358305A1
申请日:
2019.01.31
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The disclosure provides compositions and methods useful for treating glaucoma. In particular, the invention provides an adeno-associated viral (AAV)-mediated gene therapy for glaucoma in which transduced cells of the eye secrete a therapeutic protein (for example, a matrix metalloproteinase) resulting in remodeling of the extracellular matrix of the trabecular meshwork of said eye.
