The Government of the United States of America as Represented by the Secretary; Department of Health and Human Services
发明人:
Cuttitta, Frank,Martinez, Alfredo
申请号：
AU2010214693
公开号：
AU2010214693C1
申请日:
2010.08.27
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
#$%^&*AU2010214693C120140123.pdf#####ABSTRACT This invention relates, e.g., to methods for inhibiting or stimulating an activity of an adrenomedullin (AM) or gastrin releasing peptide (GRP) peptide hormone, comprising 5 contacting the peptide with a small molecule, non-peptide, modulatory agent of the invention. Complexes of these modulatory agents with other components, such as the peptides or blocking antibodies specific for the peptides, are also described, as are pharmaceutical compositions comprising the modulatory agents, and methods for using the modulatory agents to diagnose or treat patients.1/9 SUBSTRATE COLORED PRODUCT PEROXIDASE MONOCLONAL ANTIBODY A A A LIBRARY COMPOUNDS PLATE BOTTOM FIG. 1A r 1 2 3 4 5 6 7 8 9 10 11 12 A --- Tr- A B C FIG. 1B
