The United States of America; as represented by the Secretary. Department of Health and Human Serv
发明人:
Frank Cuttitta,Alfredo Martinez
申请号：
US14103605
公开号：
US20140100163A1
申请日:
2013.12.11
申请国别(地区):
US
年份:
2014
代理人:
摘要：
This invention relates, e.g., to methods for inhibiting or stimulating an activity of an adrenomedullin (AM) or gastrin releasing peptide (GRP) peptide hormone, comprising contacting the peptide with a small molecule, non-peptide, modulatory agent of the invention. Complexes of these modulatory agents with other components, such as the peptides or blocking antibodies specific for the peptides, are also described, as are pharmaceutical compositions comprising the modulatory agents, and methods for using the modulatory agents to diagnose or treat patients.
