An apparatus for cleaning, sanitization, disinfection and the like, particularly for trolleys for cleaning and other elements, comprising a casing (3) provided with at least one door (4) for accessing an inner space (5), which can be isolated from the outside as a result of closing the door (4) and which is adapted to accommodate at least one trolley for cleaning (2) and/or other elements. The trolley (2) and/or the other elements can be introduced into the space (5), and extracted therefrom, through the opening of the door (4). The space (5) is associated with at least one tank (6) of a sanitizing substance, so as to enable the spraying of the space (5) with the substance and achieve the consequent cleaning, sanitization and disinfection of the trolley (2) accommodated in the space (5).