CHEN, XI,DRAGOLI, DEAN R.,FAN, PINGCHEN,LI, YANDONG,POWERS, JAY P.,PUNNA, SREENIVAS,TANAKA, HIROKO,ZHANG, PENGLIE
申请号：
CA2883353
公开号：
CA2883353A1
申请日:
2013.08.27
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
