CHEN, XI,FAN, PINGCHEN,LI, YANDONG,POWERS, JAY P.,MALATHONG, VIENGKHAM,PUNNA, SREENIVAS,TANAKA, HIROKO,ZHANG, PENGLIE,DRAGOLI, DEAN
申请号：
CA2893597
公开号：
CA2893597A1
申请日:
2013.12.06
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are diazole lactam derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.
