Apparatus and methods are described as relating to a variable angled guide plug holder for use in interventional procedures. In an exemplary embodiment, a variable angled guide plug holder for use in interventional procedures is provided, including a guide plug holder for receiving an angular determination fixture, the guide plug holder movable relative to the angular determination fixture between a plurality of positions, each position providing a different angle of insertion relative to a point of origin on the angular determination fixture, and plate plug engaged with the angular determination fixture wherein the plate plug is insertable into a guide plate aperture of a guide plate for use in an interventional procedure.