#$%^&*AU2020204441A120200723.pdf#####ABSTRACT The invention provides compounds of Formula (1), and their use in methods for treating or preventing a protozoan infection in a subject using a compound of Formula (1). The invention also provides the use of a compound of Formula (1) in the manufacture of a medicament for the treatment of a protozoan infection in a subject. The invention further provides a medical device when used in a method of treating or preventing a protozoan infection in a subject and to a medical device comprising the composition of the invention.