The invention comprising the heretofore veterinary anti-protozoal decoquinate and one or both of a redox drug or macrolide drug for prophylaxis or treatment of Babesia and other Apicomplexan protozoa infections in humans. The decoquinate or its metabolite kill certain life stages of Babesia. The redox and macrolide drugs treat life stages and forms of Babesia that are not susceptible to the decoquinate.
