SU, WEI-GUO,苏慰国,蘇慰國,ZHANG, WEIHAN,张维汉,張維漢,LI, JINSHUI,李金水
申请号：
TW103108613
公开号：
TWI618698B
申请日:
2014.03.12
申请国别(地区):
TW
年份:
2018
代理人:
摘要：
The present invention relates to novel pyrimidine and pyridine compounds of formula (I) or a pharmaceutical acceptable salt thereof, wherein R1, R2, R3, R4, R5, X, Y and G are as defined in the description, to pharmaceutical compositions containing them, a process for preparing them, and their use in therapy of a disease responsive to inhibition of FGFR, for example, cancer.本發明涉及式(I)的新型嘧啶和吡啶類化合物或其藥學上可接受的鹽，其中R1、R2、R3、R4、R5、X、Y和G如說明書中所定義，涉及包含它們的醫藥組成物、其製備方法以及其在治療對抑制FGFR有回應的疾病如癌症中的用途。
