The present invention provides a patch and a patch preparation having an adhesive layer with a sufficient thickness, as well as appropriate skin adhesiveness and flexibility, which resist falling off from the skin even when a load is applied to the side opposite to the surface of the patch or patch preparation to be adhered to the skin, i.e., an exposed surface of a support of the patch or patch preparation, and show low irritation to the skin； an adhesive layer, which is obtained by crosslinking a liquid rubber having a crosslinkable functional group in a molecule in the presence of a crosslinking agent having a functional group number of 3 or below and a catalyst, on at least one surface of a support； and a patch preparation having an adhesive layer containing a pharmaceutical agent.
