ПАЙК Курт Гордон (GB),БАРЛАМ Бернард Кристоф (GB),ХАНТ Томас Энтони (GB),ИТЕРТОН Эндрю Джон (GB)
申请号:
RU2018120492
公开号:
RU2018120492A
申请日:
2016.11.02
申请国别(地区):
RU
年份:
2019
代理人:
摘要:
and pharmaceutically acceptable salts thereof, where R1, R2, R3 and R4 have any of the meanings defined herein. The specification also relates to the use of compounds of Formula (I) and salts thereof to treat or prevent ATM mediated disease, including cancer. The specification further relates to pharmaceutical compositions comprising substituted imidazo[4,5-c]quinolin-2-one compounds and pharmaceutically acceptable salts thereof; kits comprising such compounds and salts; methods of manufacture of such compounds and salts; and intermediates useful in such manufacture.