BRASEL KENNETH ALLAN,FOSTER STEPHEN,CERRETTI DOUGLAS PAT,SUN JILIN,SMOTHERS JAMES F,MEHLIN CHRISTOPHER
申请号:
ZA201001541
公开号:
ZA201001541B
申请日:
2010.03.03
申请国别(地区):
ZA
年份:
2015
代理人:
摘要:
Antigen binding proteins that bind to human c-fms protein are provided. Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the same are also provided. The antigen binding proteins can inhibit binding of c-fms to CSF-I, reduce monocyte migration into tumors, and reduce the accumulation of tumor-associated macrophages.