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Fluorescent probe for measuring protease
专利权人:
Tetsuo Nagano
发明人:
Tetsuo Nagano,Yasuteru Urano,Masayo Sakabe
申请号:
US13201537
公开号:
US08461358B2
申请日:
2010.02.19
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A compound represented by the formula (I) or a salt thereof (R1 represents hydrogen atom, or a substituent R2 to R7 represent hydrogen atom, hydroxyl group, an alkyl group, or a halogen atom R8 and R9 represent hydrogen atom, or an alkyl group X represents a C1-C3 alkylene group and R10 represents an acyl group), which promptly causes a structural change from a non-fluorescent closed ring structure to a strongly fluorescent open ring structure by hydrolysis of an acyl group, and is useful as a fluorescent probe for measuring a protease showing superior suitability for quantification.
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