Yosu Ion VARA SALAZAR,Eneko ALDABA ARÉVALO,Ferdinando NICOLETTI,Massimo LIBRA,Katia Domenica MANGANO
申请号:
US16347845
公开号:
US20190314334A1
申请日:
2017.11.07
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention refers to the use of compounds derived from trisubstituted 1H-pyrrole rings and aromatic rings, which have the following formula (I):whereinR1 and R2 represent, independently of each other: an optionally substituted phenyl ring, oran optionally substituted 5-membered heteroaromatic ring;one of R3 and R4 is H and the other represents agroup wherein W is OH or an ortho-aniline group;each A, independently of each other, represents a —;CH2—; group or is absent;═;Y—;Y═; is ═;HC—;CH═;, ═;N—;CH═;, or ═;HC—;N═;;or a salt or solvate thereof,in the prevention or treatment of an autoimmune disease.