BRANDENBURG, Boerries,VOGELS, Ronald,KOLKMAN, Joost, A.,FRIESEN, Robert, Heinz, Edward
申请号:
SG11201705614Q
公开号:
SG11201705614QA
申请日:
2016.02.05
申请国别(地区):
SG
年份:
2017
代理人:
摘要:
Multimeric binding molecules that are capable of specifically binding to hemagglutinin (HA) of at least two influenza A virus strains, said strains comprising HA of two different HA subtypes from phylogenetic group 2; or capable of specifically binding to hemagglutinin (HA) of at least one influenza A virus strain from phylogenetic group 1 and at least one influenza A virus strain from phylogenetic group 2; or capable of specifically binding to hemagglutinin (HA) of at least one influenza B virus strain are provided. The binding molecules preferably are also capable of neutralizing at least two influenza A virus strains from phylogenetic group 2; or capable of neutralizing at least one influenza A virus strain from phylogenetic group 1 and at least one influenza A virus strain from phylogenetic group 2; or capable of specifically neutralizing at least one influenza B virus strain.