A method is described for the prophylaxis or treatment of hypertension in a cat in need of such treatment. The method includes administration of a therapeutically effective amount of angiotensin II receptor 1 (AT-1) antagonist (sartan) to the cat, where the therapeutically effective amount of the sartan is administered in a daily dosage amount that is varied over a treatment period, the daily dosage amount of the sartan for a first period of time during the treatment period is 1.0 to 5.0 mg/kg of body weight, and the daily dosage amount of the sartan is decreased for a second period of time subsequent the first period of time during the treatment period.本發明描述一種用於預防或治療需要此治療之貓之高血壓之方法。該方法包括向該貓投與治療有效量之血管收縮素II受體1 (AT-1)拮抗劑(沙坦(sartan)),其中該沙坦之治療有效量係以在治療期內改變之每日劑量投與,在該治療期期間第一時間段該沙坦之每日劑量為1.0至5.0 mg/kg體重,且在該治療期期間第一時間段之後的第二時間段該沙坦之每日劑量減少。