FISHER, Laurel, A.,KYROU, Christos,FLORES, Ron,IANIRO, Teodoro,PARK, Sonhee, C.
申请号：
USUS2017/042661
公开号：
WO2018/017608A1
申请日:
2017.07.18
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A method is disclosed for decolorizing a muscadine pomace grape extract by processing the clarified extract by ultrafiltration through a 500-5000 kDa microfiltration membrane to obtain a first permeate in which flavor components are removed. The retentate is subjected to ultrafiltration through a 25-100 kDa ultrafiltration membrane to obtain a second permeate and a second retentate. The polymeric condensed tannins are removed in the second retentate and the second permeate is the decolorized extract having increased levels of polyphenols and lowered levels of sugars and condensed tannins compared to the first retentate. The decolorized extract can be incorporated into skin care compositions, which can also include beta-glucan and grape seed extract. The skin care compositions can and applied to the skin to maintain healthy skin without discoloration. In some embodiments, the compositions are used for reducing inflammation in the skin, including inflammation that results from exposure to ultraviolet radiation. Methods are disclosed for inhibiting the production of anti-inflammatory mediators in skin cells, and inhibiting damage induced by ultraviolet radiation by applying topical compositions which include a decolorized muscadine (Vitis rotundifolia) pomace solvent extract, beta-glucan and grape seed extract, to the skin.L'invention concerne un procédé de décoloration d'un extrait de raisin de marc de muscadine par traitement de l'extrait clarifié par ultrafiltration à travers une membrane de microfiltration de 500 à 5000 kDa pour obtenir un premier filtrat dans lequel les composants aromatiques sont éliminés. Le rétentat est soumis à une ultrafiltration à travers une membrane d'ultrafiltration de 25 à 100 kDa pour obtenir un second filtrat. Les tanins condensés polymères sont éliminés, et le second filtrat est l'extrait décoloré ayant des niveaux accrus de polyphénols et un taux réduit de sucres et de tanins condensés par rapport au premier rétentat. L'extrait décol
