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N-SUBSTITUTED-CYCLIC AMINO DERIVATIVE
专利权人:
Nobuhisa Fukuda;Yoshio Nakai;Yohei Ikuma;Hiroyuki Nakahira;Satoshi Suetsugu;Takashi Takada
发明人:
Satoshi Suetsugu,Nobuhisa Fukuda,Yoshio Nakai,Takashi Takada,Yohei Ikuma,Hiroyuki Nakahira
申请号:
US13380376
公开号:
US20120122773A1
申请日:
2010.06.24
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides a compound of formula (I):wherein R1a is optionally substituted C1-6 alkyl, etc.; R1m is hydrogen atom, etc.; G1, G2, G3 and G4 are (i), etc. ((i) G1 is —N(R1b)—, G2 is —CO—, G3 is —C(R1c)(R1d)—, and G4 is oxygen, etc.); R1b is optionally substituted C1-6 alkyl, etc.; R1c and R1d are each independently optionally substituted C1-6 alkyl, etc.; R2 is optionally substituted C1-6 alkyl, etc.; R3a, R3b, R3c and R3d are each independently a group: -A-B (A is a single bond, etc., B is hydrogen atom, etc.), etc.; n is 1, etc.; R5 is C1-4 alkoxycarbonyl, etc., or a pharmaceutically acceptable salt thereof, which is useful as a renin inhibitor.
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