A soybean cultivar designated 8595250112 is disclosed. Seeds of soybean 8595250112, the plants of soybean 8595250112, to plant parts of soybean 8595250112, and methods for producing a soybean plant produced by crossing soybean 8595250112 with itself or with another soybean variety are disclosed. Methods for producing a soybean plant containing in its genetic material one or more genes or transgenes and the transgenic soybean plants and plant parts produced by those methods are disclosed. Also disclosed are soybean cultivars, breeding cultivars, plant parts, and cells derived from soybean 8595250112, methods for producing other soybean cultivars, lines or plant parts derived from soybean 8595250112, and the soybean plants, varieties, and their parts derived from use of those methods. Also disclosed are hybrid soybean seeds, plants, and plant parts produced by crossing 8595250112 with another soybean cultivar.