АЛИ Амджад (US),ЛО Майкл Ман-Чу (US),ЛИМ Йеон-Хее (US),СТЭМФОРД Эндрю (US),КУАН Жунцзе (US),ТЕМПЕСТ Пол (CN),ЮЙ Юнун (US),ХУАН Сяньхай (US),ХЕНДЕРСОН Тимоти Дж. (US),КИМ Дзае-Хун (US),БОЙС Кристофер (
申请号：
RU2015131148
公开号：
RU2015131148A
申请日:
2013.12.20
申请国别(地区):
RU
年份:
2017
代理人:
摘要：
Disclosed are compounds of Formula G1 (structurally represented): where &ldquo；RG3&rdquo；&ldquo；Rd1&rdquo； to &ldquo；Rd4&rdquo；, &ldquo；n&rdquo；, &ldquo；m&rdquo；, &ldquo；p&rdquo；, &ldquo；W&rdquo；, &ldquo；X&rdquo；, &ldquo；Y&rdquo；, and &ldquo；Z&rdquo； are defined herein which compounds are antagonists of A2A receptor. Disclosed herein also are uses of the compounds described herein as antagonists of the A2a receptor in the potential treatment or prevention of neurological disorders and diseases in which A2A receptors are involved. Disclosed herein also are pharmaceutical compositions comprising these compounds and uses of these pharmaceutical compositions.
