UNIVERSITY OF UTAH RESEARCH FOUNDATION;BROWN, Eric, N.;PAPPAS, Christian, Matthew;HAGEMAN, Gregory, S.;HUTCHESON, David
发明人:
HAGEMAN, Gregory, S.,PAPPAS, Christian, Matthew,BROWN, Eric, N.,HUTCHESON, David
申请号：
USUS2012/035467
公开号：
WO2012/149329A3
申请日:
2012.04.27
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Described herein are methods for determining a Caucasian subject's susceptibility to having or developing a complement-mediated disease comprising determining in the Caucasian subject the identity of one or more haplotypes, wherein the one or more haplotypes are HI_62_A, H2_62_A, H3_62_A, H4_62_A, H5_62_A, H6_62_A, H7 62_A, H8 62_A, H9_62_A, HI0_62_A, HII_62_A, H12 62_A, H13_62_A, HI4_62_A, HI5_62_A, or a complement thereof, and wherein the presence of one or more of the haplotypes indicates the subject's susceptibility for having or developing a complement-mediated disease.La présente invention porte sur des procédés et des compositions pour le diagnostic et le traitement d'une maladie à médiation par le complément.
