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Methods of predicting the development of complement-mediated disease
专利权人:
University of Utah Research Foundation
发明人:
Hageman, Gregory S.,Pappas, Christian Matthew,Brown, Eric N.,Hutcheson, David
申请号:
AU2012249521
公开号:
AU2012249521A1
申请日:
2012.04.27
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Described herein are methods for determining a Caucasian subject's susceptibility to having or developing a complement-mediated disease comprising determining in the Caucasian subject the identity of one or more haplotypes, wherein the one or more haplotypes are HI_62_A, H2_62_A, H3_62_A, H4_62_A, H5_62_A, H6_62_A, H7 62_A, H8 62_A, H9_62_A, HI0_62_A, HII_62_A, H12 62_A, H13_62_A, HI4_62_A, HI5_62_A, or a complement thereof, and wherein the presence of one or more of the haplotypes indicates the subject's susceptibility for having or developing a complement-mediated disease.
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