PROBLEM TO BE SOLVED: To provide an endoscope system, a processor device, an operation method of an endoscope system, and an operation method of a processor device capable of extracting and displaying a blood vessel at a specific depth of an observation object.SOLUTION: An endoscope system 10 includes a light source 20 for generating illumination light, an imaging sensor 48 for imaging an observation object to which the illumination light is irradiated, an image signal acquisition part 53 for acquiring an image signal of violet light and an image signal of blue light, an arithmetic image signal generation part for generating an arithmetic image signal on a blood vessel at a specific depth of the observation object using the image signal of violet light and the image signal of blue light, a brightness comparison part 71 for comparing the brightness of the image signal of violet light and the image signal of blue light used for the generation of the arithmetic image signal, and a control part 72 for changing the control of the light source 20 or the imaging sensor 48 between a case in which the image signal of violet light is acquired and a case in which the image signal of blue light is acquired, using the result of comparison by the brightness comparison part 71.SELECTED DRAWING: Figure 2COPYRIGHT: (C)2016,JPO&INPIT【課題】観察対象の特定の深さにある血管を抽出及び表示することができる内視鏡システム、プロセッサ装置、内視鏡システムの作動方法、及びプロセッサ装置の作動方法を提供する。【解決手段】内視鏡システム10は、照明光を発生させる光源20と、照明光が照射された観察対象を撮像する撮像センサ48と、紫色光の画像信号と、青色光の画像信号を取得する画像信号取得部53と、紫色光の画像信号と青色光の画像信号とを用いて観察対象の特定の深さにある血管に関する演算画像信号を生成する演算画像信号生成部と、演算画像信号の生成に用いる紫色光の画像信号及び青色光の画像信号の明るさを比較する明るさ比較部71と、明るさ比較部71の比較結果を用いて、紫色光の画像信号を得る場合と青色光の画像信号を得る場合とで、光源20または撮像センサ48の制御を変更する制御部72と、を備える。【選択図】図2