ARGADE, ANKUSH,SINGH, RAJINDER,PAYAN, DONALD G.,MOLINEAUX, SUSAN,HOLLAND, SACHA J.,CLOUGH, JEFFREY,KEIM, HOLGER,BHAMIDIPATI, SOMASEKHAR,SYLVAIN, CATHERINE,ROSSI, ALEXANDER B.,LI, HUI
申请号:
DK10011119
公开号:
DK2281563T3
申请日:
2003.01.31
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signalling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signalling cascades.