HUI LI,RAJINDER SINGH,DONALD G. PAYAN,SUSAN MOLINEAUX,SACHA J. HOLLAND,JEFFREY CLOUGH,HOLGER KEIM,SOMASEKHAR BHAMIDIPATI,CATHERINE SYLVAIN,ALEXANDER B. ROSSI,ANKUSH ARGADE
申请号:
PT10011119
公开号:
PT2281563E
申请日:
2003.01.31
申请国别(地区):
PT
年份:
2013
代理人:
摘要:
The present invention provides 2,4-pyrimidinediamine compounds that inhibit the IgE and/or IgG receptor signalling cascades that lead to the release of chemical mediators, intermediates and methods of synthesizing the compounds and methods of using the compounds in a variety of contexts, including in the treatment and prevention of diseases characterized by, caused by or associated with the release of chemical mediators via degranulation and other processes effected by activation of the IgE and/or IgG receptor signalling cascades.