HWANG, JAE-KWAN,LEE, HAE JI,LEE, JAE YOUNG,SHIM, JAE-SEOK,KIM, JEONG HWAN,KIM, DO UN,CHUNG, HEECHUL,CHUNG, JAE YOUN
申请号：
EP08766506
公开号：
EP2170255A4
申请日:
2008.06.20
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
The present invention relates to a novel use of lignan compounds, which are isolated and purified from nutmeg or the aril of nutmeg for anti-wrinkle, and more particularly, the present invention relates to a novel use for anti-wrinkle of an extract of the nutmeg or an extract of the aril of the nutmeg, fragrin A, austobailignan 7, licarin E, and macelignan. The extracts and lignan compounds of the present invention have activities in suppressing collagen degradation enzyme-1 (MMP-I, matrix metalloprotei-nase-1) and formation of new collagen (type-1 procollagen), thereby having effect on inhibitng wrinkle caused by photoaging. Accordingly, the extracts and lignan compounds of the present invention may be useful for preventing or treating wrinkle caused by photoaging.
