Disclosed are: a composition for alleviating ultraviolet irradiation-induced damage, which can be used on a daily based and is stable and safe; and a pharmaceutical preparation, a cosmetic and a food composition, each of which comprises the composition. The composition for alleviating ultraviolet irradiation-induced damage contains one or more compounds selected from the group consisting of D-glutamic acid, L-glutamic acid, D-proline, D-cystine, L-cystine, and derivatives and/or salts of the aforementioned compounds. The composition can be used as an external formulation for the skin, a cosmetic composition, an anti-wrinkle agent, a sunscreen agent, a pharmaceutical composition for treating and/or preventing skin diseases, a food composition, or a pharmaceutical composition for preventing or treating cataract.本發明係開發一種可日常使用、穩定且安全之紫外線傷害減輕組合物,與包含其之醫藥品、化妝品及食品組合物。本發明提供一種紫外線傷害減輕組合物,其包含選自由D-麩胺酸、L-麩胺酸、D-脯胺酸、D-半胱胺酸及L-半胱胺酸、與該等之衍生物及/或鹽所組成之群中的1種或2種以上之化合物。上述組合物有皮膚外用劑、化妝品組合物、抗皺劑、防曬劑、皮膚病治療用及/或預防用醫藥品組合物、食品組合物、及白內障之預防或治療用醫藥品組合物之情形。