An apparatus (21) comprising a flexible elongate member (31) having proximal and distal extremities (31a,31b) and having a passageway (51) extending from the proximal extremity to the distal extremity. A handle (33) is for introducing the distal extremity of the flexible elongate member into a natural body opening of a body. A needle (61) is disposed in the passageway for movement from a retracted position disposed in the passageway to an extended position disposed out of the passageway for penetrating the wall. The needle has a distal end portion (61b) provided with at least one opening (71) and a passage (63) extends through the needle to the opening. A supply assembly (27) including at least one reservoir (92) of at least one nonaqueous solution capable of forming a nonbiodegradable solid in the body is coupled to the proximal extremity of the flexible elongate member for introducing the nonaqueous solution through the passage and the at least one opening in the needle into the wall.
