The present invention relates to compounds having general formula I characterised in thatwherein in particular: R1 represents one or a plurality of groups such as: trifluoromethyl, halogen such as F, Cl, Br, methyl, nitro. R represents nitrogen T-U represents C=C, V represents N, W represents C=O, R2 represents Cl or H, R3=H and R4=Me, A representswherein n=m=1, X represents -CH2- and E represents -CH-, and D represents oxygen, along with the various isomers and mixtures thereof in any proportions, and the pharmaceutically acceptable salts thereof.本發明係關於具通式I之化合物,其特徵在於其中尤其:R1代表一或複數個基團,例如:三氟甲基;鹵素,例如F、Cl、Br;甲基、硝基。R代表氮T-U代表C=C,V代表N,W代表C=O,R2代表Cl或H,R3=H且R4=Me,A代表其中n=m=1,X代表-CH2-且E代表-CH-,D代表氧,連同各式異構物及其呈任何比例之混合物,及其藥學上可接受之鹽。