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Small molecule modulators of Trp-p8 activity
专利权人:
DENDREON CORPORATION
发明人:
MORENO, OFIR,NATARAJAN, SATEESH,DUNCAN, DAVID F.
申请号:
DK07750861
公开号:
DK1986622T3
申请日:
2007.02.15
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
Provided are small-molecule Trp-p8 modulators, including Trp-p8 agonists and Trp-p8 antagonists, and compositions comprising small-molecule Trp-p8 agonists as well as methods for identifying and characterizing novel small-molecule Trp-p8 modulators and methods for decreasing viability and/or inhibiting growth of Trp-p8 expressing cells, methods for activating Trp-p8-mediated cation influx, methods for stimulating apoptosis and/or necrosis, and related methods for the treatment of diseases, including cancers such as lung, breast, colon, and/or prostate cancers as well as other diseases, such as benign prostatic hyperplasia, that are associated with Trp-p8 expression.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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