#$%^&*AU2018201316B220180809.pdf#####ABSTRACT Described herein is a system and method of controlling real-time image-guided adaptive radiation treatment of at least a portion of a region of a patient. The computerimplemented method comprises obtaining a plurality of real-time image data corresponding to 2-dimensional (2D) magnetic resonance imaging (MRI) images including at least a portion of the region, performing 2D motion field estimation on the plurality of image data, approximating a 3-dimensional (3D) motion field estimation, including applying a conversion model to the 2D motion field estimation, determining at least one real-time change of at least a portion of the region based on the approximated 3D motion field estimation, and controlling the treatment of at least a portion of the region using the determined at least one change.WO 2016/094284 PCT/US2015/064229 3/5 00 0L 00 ~~0 000. Q co o ) 0 ) 00 00 0i M j 0 LL 0 LI m m
