MACDONALD, LYNN,MURPHY, ANDREW J.,TU, NAXIN,VORONINA, VERA,GURER, CAGAN
申请号：
CA2900832
公开号：
CA2900832A1
申请日:
2014.02.20
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The invention provides genetically modified non-human animals that express chimeric human/non-human T cell co-receptor polypeptides (e.g., CD4, CD8a, CD8ß ), as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified animals and methods of making the same.
