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USES OF AND METHODS OF TREATMENT WITH CYSTATHIONINE
专利权人:
发明人:
KENNETH MACLEAN,RICHARD AUSTIN
申请号:
US15800840
公开号:
US20180050004A1
申请日:
2017.11.01
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to uses of and methods of treatment with cystathionine. In one embodiment, cystathionine reduces the development of toxin-induced liver and/or kidney disease induced by homocystinuria and/or acute nephropathy. In one embodiment, a cystathionine synthesis inhibitor is administered to increase tumor cell apoptosis and/or increase the efficacy of chemotherapeutic treatment. More particularly, cystathionine can protect cells against toxin-induced cellular apoptosis and/or cystathionine synthesis inhibitors can increase neuroblastoma cell kill rates during chemotherapy.
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