ARNELLE, Derrick,DEAVER, Daniel,DEAN, Reginald, L., III,TODTENKOPF, Mark
申请号：
EP20090710456
公开号：
EP2252150(B1)
申请日:
2009.02.13
申请国别(地区):
欧洲专利局
年份:
2018
代理人:
摘要：
The present invention relates to compounds of Formula I or II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which relates to morphinan compounds useful as μ, δ, and/or &kgr; receptor opioid compounds and pharmaceuticals containing same that may be useful for mediating analgesia, combating drug addiction, alcohol addiction, drug overdose, mental illness, bladder dysfunctions, neurogenic bladder, interstitial cystitis, urinary incontinence, premature ejaculation, inflammatory pain, peripherally mediated and neuropathic pain, cough, lung edema, diarrhea, cardiac disorders, cardioprotection, depression, and cognitive, respiratory, diarrhea, irritable bowel syndrome and gastro-intestinal disorders, immunomodulation, and anti-tumor agents.
