The present invention relates to a device for draining lymph into vein, which comprises: a storage chamber including a chamber wall, wherein a storage space formed by the chamber wall, and at least one first opening and a second opening are formed on the chamber wall at least one osmosis membrane disposed at the first opening so that lymph can penetrate into the storage space, wherein the osmosis membrane is made of negative charged polymer molecules a first conduit, of which one end connects to the storage space, and the other end connects with a vein so that the space can connect with the vein and a pump provided in the storage chamber, wherein a negative pressure in the storage space is generated by the pump to drain lymph into the vein.