FUSION PROTEINS FROM FRAGMENTS OF HUMAN PROTEINS FOR OBTAINING COMPOSITIONS OF MULTIPLE MULTIMERIZED FC IMMUNOGLOBULINS WITH IMPROVED BINDING WITH THE FC RECEPTOR

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专利权人:

ГЛИКНИК ИНК. (US)

发明人:

БЛОК, Дэвид С. (US),ОЛСЕН, Хенрик (US)

申请号：

RU2019104724

公开号：

RU2019104724A

申请日:

2017.07.24

申请国别(地区):

RU

年份:

2020

代理人:

摘要：

The present invention involves a series of fully recombinant multimerized forms of immunoglobulin Fc which thereby present polyvalent immunoglobulin Fc to immune cell receptors. The fusion proteins exist as both homodimeric and highly ordered multimeric fractions, termed stradomers. The invention involves fusion proteins that bind to FcγRs and complement and that are useful in the treatment and prevention of disease.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/