The present invention provides a Bacillus subtilis strain (Bacillus subtilis, Accession No. KCTC 13020 BP) which produces a thrombolytic enzyme at a high yield. The Bacillus subtilis GDN strain according to the present invention has markedly higher thrombolytic enzyme producing ability than the conventional Bacillus natto bacteria such as Miyagino bacteria and when intake of natto produced by the Bacillus subtilis GDN strain of the present invention , The activity of the thrombolytic enzyme is similarly kept even if the intake of natto is reduced to about one fifth compared with the case of ingesting natto produced by the conventional Bacillus natto bacteria and the intake of vitamin K 2 is, The Bacillus subtilis GDN strain can be effectively utilized for the production of various foods intended for thrombolysis, since it can be adjusted within the limit value of the recommended daily amount.本発明は、血栓溶解酵素を高生産するバチルス・サブチリス菌株(Bacillus subtilis、受託番号KCTC13020BP)を提供する。本発明によるバチルス・サブチリスGDN菌株は、宮城野菌のような従来の納豆菌に比べて、血栓溶解酵素の生産能が顕著に高く、本発明のバチルス・サブチリスGDN菌株で製造した納豆を摂取する場合、従来の納豆菌によって製造した納豆を摂取する場合に比べて、納豆の摂取量を5分の1程度に減らしても、血栓溶解酵素の活性は同様に保持し、ビタミンK2の摂取量は、1日勧奨量の限界値内に調節することができて、バチルス・サブチリスGDN菌株は、血栓溶解を目的とした多様な食品の製造のために効果的に活用が可能である。
