Eben Alsberg,Anna D. Dikina,Marsha W. Rolle,Hannah A. Strobel
申请号：
US15698429
公开号：
US20180064851A1
申请日:
2017.09.07
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate includes a plurality of cells and a plurality of biocompatible and biodegradable nanoparticles and/or microparticles that are incorporated within the cell aggregates. The nanoparticles and/or microparticles acting as a bulking agent within the cell aggregate to increase the cell aggregate size and/or thickness and improve the mechanical properties of the cell aggregate as well as to deliver bioactive agents.
