HIGH-THROUGHPUT MOUSE MODEL FOR OPTIMIZING ANTIBODY AFFINITIES

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专利权人:

CHILDREN'S MEDICAL CENTER CORPORATION

发明人:

ALT Frederick W.,CHENG Hwei-Ling,TIAN Ming

申请号：

US201816017221

公开号：

US2018295822(A1)

申请日:

2018.06.25

申请国别(地区):

美国

年份:

2018

代理人:

摘要：

Described herein are compositions (e.g. cells and transgenic animals) and methods relating to engineered Ig loci that permit expression of particular antibodies or antibody segments while still permitting recombination and/or maturation process for antibody optimization.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/