The invention provides a method for treating various types of cancer/tumor by administering the combination of SDF-1 antagonist, in particular, that specifically binds to human CXCR4, and another chemotherapeutic agent, or a radiation therapy, during an embolization therapy. Such combination therapies exhibit synergistic effects compared to the treatment with either agent alone. Thus, the method of the invention is particularly beneficial for cancer patients who have low tolerance to the side effects caused by high dosages required for the treatment by either agent alone.本發明提供於栓塞療法期間,藉投予SDF-1拮抗劑,更明確言之,特異性地結合至人類CXCR4的SDF-1拮抗劑與另一種化學治療劑或放射線治療之組合用於治療各型癌症/腫瘤之方法。此種組合療法比較單獨使用任一種治療劑具有協同增效效果。如此,本發明之方法用於對單獨使用任一種治療劑治療所需高劑量造成的副作用具有低耐受性的癌症病人特別有用。