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Tablet containing 1 cyclopropyl 8 (difluoromethoxy) 7 [(1r) 1 methyl 2 3 dihydro 1h isoindole 5 yl] 4 oxo 1 4 dihydroquinoline 3 carboxylic acid methanesulfonic acid hydrate
专利权人:
发明人:
KAKUDA SAHOE,MIYAZAKI TSUTOMU,OKADA KOTARO
申请号:
IN4407/DELNP/2014
公开号:
IN2014DN04407A
申请日:
2014.05.30
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
(1) A tablet according to the present invention has a percentage content of 1-cyclopropyl-8-(difluoromethoxy)-7-[(1R)-1-methyl-2,3-dihdro-1H-isoindole-5-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonic acid hydrate of between 80 wt% and 97.5 wt%. (2) The tablet is smaller is size than 200mg of a commercially available Geninax tablet. (3) As a result, drug compliance is improved, (4) leachability is high, and (5) hardness and friability are high. (6) As a result, the present invention withstands film coating and transportation, and is useful as a tablet of methanesulfonic acid hydrate of chemicals compound A.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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