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solid forms of 3- (6- (1- (2-, 2-difluorbenzo [d] [1,3] dioxol-5-yl) cyclopropanecarboxamido) -3-methylpyridin-2-yl) benzoic acid
专利权人:
Vertex Pharmaceuticals Incorporated
发明人:
Ali Keshavarz-Shokri,Beili Zhang,Mariusz Krawiec
申请号:
BR112012026257
公开号:
BR112012026257A2
申请日:
2011.04.07
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
solid forms of 3- (6- (1- (2-, 2-difluorbenzo [d] [1,3] dioxol-5-yl) cyclopropanecarboxamido) -3-methylpyridin-2-yl) benzoic acid. The present invention substantially relates to a solid form of 3- (6- (1- (2,2-difluorbenzo [d] [1,3] dioxol-5-yl) cyclopropanecarboxamido) -3-methylpyridin-2-yl acid ) benzoic (compound 1 as solvate and compound 1 as hc1 salt), processes for making such forms, pharmaceutical compositions thereof and methods of treating them.formas sólidas de ácido 3-(6-(1-(2-,2-difluorbenzo[d][1,3]dioxol-5-il)ciclopropanocarboxamido)-3-metilpiridin-2-il)benzóico. a presente invenção se refere substancialmente a uma forma sólida do ácido 3-(6-(1-(2,2-difluorbenzo[d][1,3]dioxol-5-il)ciclopropanocarboxamido)-3-metilpiridin-2-il) benzóico (composto 1, sob a forma a de solvato e composto 1, soba a forma a de sal de hc1), aos processos para fabricação de tais formas, às composições farmacêuticas dos mesmos e aos métodos de tratamento com as mesmas.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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