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Extended-release oral dosage forms for poorly soluble amine drugs
专利权人:
Yanming Zu
发明人:
Yanming Zu,Sudhir Gorukanti,Salah Uddin Ahmed
申请号:
US12900205
公开号:
US09011912B2
申请日:
2010.10.07
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Oral dosage forms for poorly soluble amine drugs are provided. Such dosage forms include an ionizable compound such as an organic acid, an amphiphilic polymer and a release rate-controlling membrane. Such dosage forms allow for the consistent release of the active agent in both gastric pH conditions and in the intestine. Methods of making such dosage forms are also provided.
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