Verne Earle Cowles,Sui Yuen Eddie Hou,Bret Berner,Chien-Hsuan Han,Ryan Douglas Fell,Chunhong Gu
申请号:
US14838031
公开号:
US20160038411A1
申请日:
2015.08.27
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Dosage forms for delayed and pulsed release of therapeutic agents into the stomach are described. The dosage forms are gastric retentive dosage forms that achieve release of the therapeutic agent into the stomach and upper gastrointestinal tract subsequent to administration of the dosage form. The dosage forms find particular use in administration of acid-labile active agents such as proton pump inhibitors, and in treating gastric acid secretion such as gastro-esophageal reflux disease (GERD) and nocturnal acid breakthrough (NAB).