The General Hospital Corporation;Fluoropharma, Inc.
发明人:
David R. Elmaleh,Timothy M. Shoup,Hongning Fu
申请号:
US13903362
公开号:
US20130315827A1
申请日:
2013.05.28
申请国别(地区):
US
年份:
2013
代理人:
摘要:
One aspect of the present invention relates to compounds, compositions and methods for diagnosis and/or treatment of a subject suffering from an amyloidosis-associated pathological condition. In certain embodiments, the imaging and/or therapeutic agents of the instant invention may be administered to a subject for identification and/or treatment of amyloid deposits. A specific imaging method detects amyloid deposits by administering the imaging agent to the subject and detecting the spatial distribution of the agent. Differential accumulation of the agent is indicative of AD or an amyloidosis-associated pathological condition and can be monitored by using a PET or SPECT camera.