Compounds and compositions for detection and treatment of Alzheimer's disease and related diseases

• 收藏
• 分享

专利权人:

ザ ジェネラル ホスピタル コーポレイション;フルオロフアーマ・インコーポレーテツド;ザ ジェネラル ホスピタル コーポレイション

发明人:

エルマレー，デイビツド・アール,シヤウプ，テイモシー,フー，ホンニン,エルマレー,デイビツド・アール,シヤウプ,テイモシー,フー,ホンニン

申请号：

JP2011501009

公开号：

JP5501339B2

申请日:

2009.03.23

申请国别(地区):

JP

年份:

2014

代理人:

摘要：

One aspect of the present invention relates to compounds of formula (II), compositions and methods for diagnosis and/or treatment of a subject suffering from an amyloidosis-associated pathological condition. In certain embodiments, the imaging and/or therapeutic agents of the instant invention may be administered to a subject for identification and/or treatment of amyloid deposits. A specific imaging method detects amyloid deposits by administering the imaging agent to the subject and detecting the spatial distribution of the agent. Differential accumulation of the agent is indicative of AD or an amyloidosis-associated pathological condition and can be monitored by using a PET or SPECT camera.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/