A method for characterizing tissue of a patient, including receiving acoustic data derived from the interaction between the tissue and the acoustic waves irradiating the tissue generating a morphology rendering of the tissue from the acoustic data, in which the rendering represents at least one biomechanical property of the tissue determining a prognostic parameter for a region of interest in the rendering, in which the prognostic parameter incorporates the biomechanical property and analyzing the prognostic parameter to characterize the region of interest. In some embodiment, the method further includes introducing a contrast agent into the tissue generating a set of enhanced morphology renderings of the tissue after introducing the contrast agent determining an enhanced prognostic parameter from the enhanced morphology renderings and analyzing the enhanced prognostic parameter.
