A method is described for generating contrast medium-aided CT image data from an examination region of a patient. At least two sets of projection measurement data assigned to different X-ray energy spectra are acquired from the examination region. At least two different contrast media are present simultaneously during the acquisition in the examination region. Furthermore, at least two separate image datasets are reconstructed based upon the at least two sets of projection measurement data with the aid of a multi-material decomposition. Each of the at least two separate image datasets is assigned to one of the at least two contrast media and the materials according to which decomposition takes place are the respective contrast media. Additionally a method for analyzing morphological and/or functional parameters assigned to different contrast media in an examination region of a patient is described. Furthermore an image reconstruction device and a computed tomography system is described.
