Ann Marie SCHMIDT,Ravichandran RAMASAMY,Alexander SHEKHTMAN,Vivek RAI,Michaele B. MANIGRASSO
申请号：
US16094270
公开号：
US20190194136A1
申请日:
2017.04.18
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Quinoline compounds are disclosed that have a formula represented by the following:and wherein Cy, R1, R4a, R4b, and n are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, diabetes complications, inflammation, and neurodegeneration, obesity, cancer, ischemia/reperfusion injury, cardiovascular disease and other diseases related to RAGE activity.
